
South Carolina Lowcountry Vacation Packages
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Your South Carolina Lowcountry Vacation
Whether you're visiting South Carolina Lowcountry for its rich history, coastal scenery or something else entirely, this is one destination you'll never forget. Create your ultimate break with one of our South Carolina Lowcountry vacation packages. With so many things to see on a trip to South Carolina Lowcountry, it can be difficult to know where to start. Kick off your journey in Beaufort at Bay Street and The Sands — two popular attractions here. Another great city worthy of a spot on your itinerary is Walterboro - St. George. Don't miss The Forde Doll & Doll House Collection and South Carolina Artisans Centre. Expedia has hotels, flights and all your other travel needs to help you create your own tailored South Carolina Lowcountry vacation today.
Top South Carolina Lowcountry Vacation Deals

Water's Edge Inn - Adults Only
Reviewed on Jun 8, 2026

Emeline
Reviewed on Jun 23, 2026

The Ryder Hotel
Reviewed on Jun 23, 2026

Thompson Savannah, by Hyatt
Reviewed on Jun 18, 2026

JW Marriott Savannah Plant Riverside District
Reviewed on Jun 24, 2026
Where to stay in South Carolina Lowcountry

Edisto Beach
You'll enjoy the beaches and riverfront in Edisto Beach. You might want to make time for a stop at Edisto Beach State Park or Plantation Course at Edisto.
South Carolina Lowcountry Hotel Deals

Sonesta Resort Hilton Head Island
"Traveled her last year and had an amazing time. This time not so much. They changed the menu at the sea creast, not"
Reviewed on Jun 23, 2026

Hilton Beachfront Resort & Spa Hilton Head Island
"Very nice property with large pools and easy access to the beach. Room was a little dated and could have been cleaned a little better, but the staff and servers were very courteous and friendly. Overall a great place to stay!"
Reviewed on Jun 25, 2026

Beach House Resort Hilton Head
What to do in South Carolina Lowcountry

Murrells Inlet by Moonlight: Legends & Lores of the Inlet

Myrtle Beach to Charleston with Horse & Carriage Ride, Harbor Cruise, Boone Hall

Full Moon Ghost Stories Cruise in Murrells Inlet
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- Bay Street
- Botany Bay Plantation Heritage Preserve and Wildlife Management Area
- Brighton Beach Vacations
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